IN PREPARATION
Title and authors: tentative
Madison Scott*, Joseph Jansen*, Tracie Dunn*, and Han-A Park, Lycopene Promotes Neurite Development by Improving Energy in Primary Hippocampal Neurons.
Han-A Park, Megan Scott*, Mary Margaret Hayden*, Garret Burnett*, Emma Amjad*, and Amy Ellis. Effect of Oral Supplementation of Fucoxanthin in the Lung of Middle-Aged Sprague-Dawley Rats
Katelyn E. Senkus*, Maria Azrad, Anneliese Bolland, Han-A Park, Johnny R. Tice, Meijuan Zhang, Taiming Liu, Arlin B. Blood, William Van Der Pol, Casey Morrow, and Kristi M. Crowe-White. Functional mouth rinse containing inorganic nitrate and antioxidants bolsters the enterosalivary pathway and lowers blood pressure in Wistar rats
Submitted to Free Radical Biology & Medicine (March 28 2024)
Spenser R. Brown*, Margaret E. Kapperman*, Joseph T. Danner*, Han-A Park, Steven T. Weinman, and Yonghyun Kim. Extracellular Vesicle-Mediated Maintenance of Stemness in Breast Cancer Metastasis.
Submitted to Biotechnology Journal (Feb 2024)
Khondoker Adeba Ferdous*, Joseph Jansen*, Emma Amjad*, Eliana Pray*, Rebecca Bloch*, Alex Benoit*, Meredith Callahan*, Han-A and Park. Mitochondrial Protective Potential of Fucoxanthin in Brain Disorders
Submitted to Journal of Nutritional Science (November 30, 2023; Revision Sub Mar 28 2024)
Han-A Park, Emma Amjad*, Garrett Burnett*, Khondoker Adeba Ferdous*, Madison Scott*, Joseph Jansen*, Sydni Bannerman*, Megan Scott*, Robert N. Correll, Lukasz Ciesla, and Amy Ellis. The Effects of Oral Supplementation with Fucoxanthin on the Brian of Middle-Aged Sprague-Dawley Rats.
Submitted to Journal of Medicinal Food (August 2023)
PUBLICATIONS
* denotes UA students
32. Khondoker Adeba Ferdous*, Linda L. Knol, and Han-A Park. Response to the Letter to the Editor on the Association between Selenium Intake and Cognitive Function among Older Adults in the US: National Health and Nutrition Examination Surveys 2011-2014
Journal of Nutritional Science (Accepted, Sep 2023)
31. Han-A Park and Kristi M. Crowe-White. Oxidative Stress, Antioxidant Defense, and Neurodegeneration. Brain Disorders. 2023. Editorial
30. Khondoker Adeba Ferdous*, Sorour Sarihi*, and Amy C. Ellis, and Han-A Park. Neuroprotective Potential of Brown Seaweed Phytochemicals in Rodent Models of Cerebral Ischemia. Journal of Medicinal Food. 2023 Jul;26(7):436-444. doi: 10.1089/jmf.2023.0058. PMID: 37405739
29. Khondoker Adeba Ferdous*, Linda L Knol, and Han-A Park. Association between Selenium Intake and Cognitive Function among Older Adults in the US: National Health and Nutrition Examination Surveys 2011-2014. Journal of Nutritional Science. 2023 May 10;12:e57. doi: 10.1017/jns.2023.43. PMID:37180486. PMCID: PMC10173086.
28. J. Brucker Nourse, Jr.*, Shannon N. Russell, Nathan A. Moniz, Madison Scott, Han-A Park, Kim A. Caldwell, and Guy A. Caldwell. Integrated Regulation of Dopaminergic and Epigenetic Effectors of Neuroprotection in Parkinson's Disease Models PNAS, 2023 Feb 14;120(7):e2210712120. doi: 10.1073/pnas.2210712120. PMID: 36745808
27. Amy Ellis, Chuong Bui, Christine Ferguson, Deniz Azarmanesh, and Han-A Park. Associations between self-reported symptoms of SARS-CoV-2 and dietary supplement use over the previous year during the first pandemic wave. Journal of Nutritional Science 2023;12:e4. doi: 10.1017/jns.2022.115. eCollection 2023. PubMed PMID: 36721723; PubMed Central PMCID: PMC9869091.
26. Han-A Park, Spenser R. Brown*, Joseph Jansen*, Tracie Dunn*, Madison Scott*, Nelli Mnatsakanyan, Elizabeth A. Jonas, and Yonghyun Kim. Fluid Shear Stress Enhances Breast Cancer Cell Survival via Downregulation of the c-subunit of the F1Fo ATP Synthase. Biochemical and Biophysical Research Communications 2022 Sep 29;632:173-180. doi: 10.1016/j.bbrc.2022.09.084. PMID: 36209586
25. Han-A Park, Kristi M. Crowe-White, Lukasz Ciesla, Madison Scott*, Sydni Bannerman*, Abigail U. Davis*, Bishnu Adhikari*, Garret Burnett*, Katheryn Broman*, Khondoker Adeba Ferdous*, Kimberly H. Lackey, Pawel Licznerski, and Elizabeth A. Jonas. Alpha-Tocotrienol Enhances Arborization of Primary Hippocampal Neurons via Upregulation of Bcl-xL. Nutrition Research 2022 Mar 7;101:31-42. doi: 10.1016/j.nutres.2022.02.007. PMID: 35366596. PMCID: MC9081260
24. Inhyeok Chung, Han-A Park, Jun Kang, Heyyoung Kim, Su Min Hah, Juhee Lee, Hyeon Soo Kim, Won-Seok Choi, Ji Hyung Chung, and Min-Jeong Shin. Neuroprotective effects of ATPase inhibitory factor 1 preventing mitochondrial dysfunction in Parkinson's disease.
Scientific Reports 2022 Mar 9;12(1):3874. doi: 10.1038/s41598-022-07851-8. PMID: 35264673. PMCID: PMC8907304.
23. Nelli Mnatsakanyan, Han-A Park, Jing Wu, Xiang He, Marc Llaguno, Maria Latta, Paige Miranda, Besnik Murtishi, Morven Graham, Richard J Levy, Evgeny V Pavlov, and Elizabeth A. Jonas. Mitochondrial ATP synthase c-subunit leak channel triggers cell death upon loss of its F1 subcomplex. Cell Death & Differentiation. 2022. Mar 23. doi: 10.1038/s41418-022-00972-7. PMID: 35322203.
22. Joseph Jansen*, Madison Scott*, Emma Amjad*, Allison Stumpf*, Kimberly H. Lackey, Kim A. Caldwell, and Han-A Park. Bcl-xL Is Required by Primary Hippocampal Neurons During Development to Support Local Energy Metabolism at Neurites. Biology. 2021 Aug; 10(8): 772. PMID: 34440004. PMCID: PMC8389656.
21. Han-A Park, Allison Stumpf*, Katheryn Broman*, Joseph Jansen*, Tracie Dunn*, Madison Scott*, and Kristi M. Crowe-White. Role of Lycopene in Mitochondrial Protection during Differential Levels of Oxidative Stress in Primary Cortical Neurons. Brain Disorders. 2021 Sep; 3:100016. doi: 10.1016/j.dscb.2021.100016.
20. Han-A Park, Katheryn Broman*, and Elizabeth A. Jonas. Oxidative Stress Battles Neuronal Bcl-xL in a Fight to the Death. Neuronal Regeneration Research. 2021 Jan;16(1):12-15. doi: 10.4103/1673-5374.286946. PMID: 32788441. PMCID: PMC7818872.
19. Pawel Licznerski, Han-A Park, Harshvardhan Rolyan, Rongmin Chen, Nelli Mnatsakanyan, Paige Miranda, Morven Graham, Jing Wu, Nicole Cruz-Reyes, Nikita Mehta, Sana Sohail, Jorge Salcedo, Erin Song, Charles Effman, Samuel Effman, Lucas Brandao, Nancy Xu, Amber Braker, Valentin K. Gribkoff, Richard J. Levy and Elizabeth Ann Jonas. ATP synthase c-subunit leak causes aberrant cellular metabolism in Fragile X syndrome. Cell . 2020 Sep 3;182(5):1170-1185.e9. doi: 10.1016/j.cell.2020.07.008. PMID: 32795412. PMCID: PMC7484101.
18. Han-A Park, Mary Margaret Hayden*, Sydni Bannerman*, Joseph Jansen*, and Kristi M. Crowe-White, Anti-Apoptotic Effects of Carotenoids in Neurodegeneration. Molecules. 2020 Jul 29;25(15):3453. doi: 10.3390/molecules25153453. PMID: 32751250. PMCID: PMC7436041.
17. Han-A Park, Spenser R. Brown*, and Yonghyun Kim. Cellular Mechanisms of Circulating Tumor Cells during Breast Cancer Metastasis. International Journal of Molecular Sciences. 2020 Jul 17;21(14):5040. doi: 10.3390/ijms21145040. PMID: 32708855. PMCID: PMC7404335.
16. Han-A Park and Amy C. Ellis, Dietary Antioxidants and Parkinson's Disease. Antioxidants. 2020 Jul 1;9(7):570. doi: 10.3390/antiox9070570. PMID: 32630250. PMCID: PMC7402163.
15. Han-A Park, Nelli Mnatsakanyan, Katheryn Broman*, Abigail U. Davis*, Jordan May*, Pawel Licznerski, Kristi M. Crowe-White, Kimberly H. Lackey, and Elizabeth A. Jonas. Alpha-Tocotrienol Prevents Oxidative Stress-Mediated Post-Translational Cleavage of Bcl-xL in Primary Hippocampal Neurons. International Journal of Molecular Sciences. 2019 Dec 28;21(1):220. doi: 10.3390/ijms21010220. PMID: 31905614. PMCID: PMC6982044.
Pubmed Journal website PDF Media
14. Rongmin Chen, Han-A Park, Nelli Mnatsakanyan, Yulong Niu, Pawel Licznerski, Jing Wu, Paige Miranda, Morven Graham, Jack Tang, Anita Boon, Giovanni Cossu, Wim Mandemakers, Vincenzo Bonifati, Peter Smith, Kambiz Alavian, Vincenzo Bonifati, and Elizabeth A. Jonas. Parkinson’s Disease protein DJ-1 regulates ATP synthase protein components to increase neuronal process outgrowth. Cell Death & Disease. 2019 Jun 13;10(6):469. doi: 10.1038/s41419-019-1679-x. PMID: 31197129. PMCID: PMC6565618.
13. Han-A Park, Katheryn Broman*, Allison Stumpf*, Sara Kazyak*, and Elizabeth A. Jonas. Nutritional Regulators of Bcl-xL in the Brain. Molecules. 2018 Nov 19;23(11):3019. doi: 10.3390/molecules23113019. PMID: 30463183. PMCID: PMC6278276.
12. Han-A Park and Elizabeth A. Jonas. ΔN-Bcl-xL, a therapeutic target for neuroprotection. Neural Regeneration Research. 2017 Nov;12(11):1791-1794. doi: 10.4103/1673-5374.219033. PMID: 29239317. PMCID: PMC5745825.
11. Han-A Park, Pawel Licznerski, Nelli Mnatsakanyan, Yulong Niu, Silvio Sacchetti, Jing Wu, Brian M. Polster, Kambiz N. Alavian, and Elizabeth A. Jonas. Inhibition of Bcl-xL prevents pro-death actions of ΔN-Bcl-xL at the mitochondrial inner membrane during glutamate excitotoxicity. Cell Death & Differentiation. 2017 Nov;24(11):1963-1974. doi: 10.1038/cdd.2017.123. PMID: 28777375. PMCID: PMC5635221.
10. Han-A Park, Pawel Licznerski, Kambiz N. Alavian, Marya Shanabrough, and Elizabeth A. Jonas. Bcl-xL is necessary for neurite outgrowth in hippocampal neurons. Antioxidants & Redox Signaling. 2015 Jan 10;22(2):93-108. doi: 10.1089/ars.2013.5570. PMID: 24787232. PMCID: PMC4281845.
9. Hongmei Li, Han-A Park, and Elizabeth A. Jonas. Measurement of synaptic activity using fluorescent synaptopHluorin in isolated hippocampal neurons. Bio-Protocol. 2014 Dec 5;4(23):e1304. doi: 10.21769/bioprotoc.1304. PMID: 27446978. PMCID: PMC4950945.
8. Han-A Park and Elizabeth A. Jonas. Mitochondrial membrane protein Bcl-xL, a regulator of adult neuronal growth and synaptic plasticity: multiple functions beyond apoptosis. Neural Regeneration Research. 2014 Oct 1;9(19):1706-7. doi: 10.4103/1673-5374.143413. PMID: 25422630. PMCID: PMC4238157. Review
7. Kambiz N. Alavian, Gisela Beutner, Emma Lazrove, Silvio Sacchetti, Han-A Park, Pawel Licznerski, Hongmei Li, Panah Nabili, Kathryn Hockensmith, Morven Graham, George A. Porter, and Elizabeth A. Jonas. An uncoupling channel within the c-subunit ring of the F1FO ATP synthase is the mitochondrial permeability transition pore. PNAS. 2014 Jul 22;111(29):10580-5. doi: 10.1073/pnas.1401591111. PMID: 24979777. PMCID: PMC4115574.
6. Elizabeth A. Jonas, Silvio Sacchetti, Han-A Park, Emma Lazrove, Gisela Beutner, George A. Porter, and Kambiz A. Alavian. The c-subunit of the ATP synthase forms the pore of the PTP. Biophysical Journal. 106, 3a-4a (2014)
5. Han-A Park, Natalia Kubicki, Surya Gnyawali, Yuk Cheung Chen, Sashwati Roy, Savita Khanna, and Chandan K. Sen. Natural vitamin E α-tocotrienol protects against ischemic stroke by induction of multidrug resistance-associated protein 1. Stroke. 2011 Aug;42(8):2308-14.
doi: 10.1161/STROKEAHA.110.608547. PMID: 21719775. PMCID: PMC3362046.
4. Gayle Gordillo, Huiquing Fang, Han-A Park, and Sashwati Roy. Nox-4-dependent nuclear H2O2 drives DNA oxidation resulting in 8-OHdG as urinary biomarker and hemangioendothelioma formation. Antioxidants & Redox Signaling. 2010 Apr 15;12(8):933-43.
doi: 10.1089/ars.2009.2917. PMID: 19817625. PMCID: PMC2935344.
3. Han-A Park, Savita Khanna, Cameron Rink, Surya Gnyawali, Sashwati Roy, and Chandan K. Sen. Glutathione disulfide induces neural cell death via a 12-lipoxygenase pathway. Cell Death & Differentiation. (2009) 16(8):1167-79. doi: 10.1038/cdd.2009.37. PMID: 19373248. PMCID: PMC2990696.
2. Savita Khanna, Han-A Park, Chandan K. Sen, Trimurtulu Golakoti, Krishanu Sengupta, Somepalli Venkateswarlu, and Sashwati Roy. Neuroprotective and antiinflammatory properties of a novel demethylated curcuminoid. Antioxidants & Redox Signaling. 2009 Mar;11(3):449-68. doi: 10.1089/ars.2008.2230. PMID: 18724833. PMCID: PMC2787730.
1. Savita Khanna, Sashwati Roy, Han-A Park, and Chandan K. Sen. Regulation of c-Src activity in glutamate-induced neurodegeneration. Journal of Biological Chemistry. 2007 Aug 10;282(32):23482-90. doi: 10.1074/jbc.M611269200. PMID: 17569670.
BOOK CHAPTERS
4. Katheryn Broman*, Abigail U. Davis*, Jordan May*, and Han-A Park. Lifestyle factors, Mitochondrial Dynamics, and Neuroprotection in Neuroprotection - New Approaches and Prospects. London, UK, Intech. (2019)
3. Han-A Park, and Elizabeth A. Jonas. Mitochondrial Regulators of Synaptic Plasticity in the Ischemic Brain in Synaptic Plasticity. London, UK, Intech. p39-67 (2017)
2. Elizabeth A. Jonas, George A. Porter, Gisela Beutner, Nelli Mnatsakanyan, Han-A Park, Nikita Mehta, Rongmin Chen, Kambiz A. Alavian. The mitochondrial permeability transition pore: molecular structure and function in health and disease in Molecular Basis for Mitochondrial Signaling. New York City, NY, Springer Publishing. p69-105 (2017)
1. Han-A Park, Sashwati Roy, Savita Khanna, and Chandan K. Sen. Current Technologies in Single Cell Microinjection and Application to Study Signal Transduction in Method in Redox Signaling. Larchmont, NY, Mary Ann Liebert, Inc. p71-77 (2010)